第三代Buchwald預(yù)催化劑Davephos Pd G3，是各種交叉偶聯(lián)反應(yīng)的多功能催化劑。使用鈀(0)預(yù)催化劑可實(shí)現(xiàn)與芳基鹵化物與硼酸化合物的***效Suzuki-Miyaura反應(yīng)交叉偶聯(lián)。用于Buchwald-Hartwig構(gòu)建C-N鍵。用于氨基化和烷氧基化反映。硼酸的氯磺?；：铣蓆ert-butyl4-(4-((4-(3-(2-fluoro-5-(hydroxymethyl)pyridin-4-yl)ureido)pyridin-2-yl)ethynyl)phenyl)piperidine-1-carboxylate（叔丁基4-(4-(4-(3-(2-氟-5-(羥甲基)吡啶-4-基)脲基)吡啶-2-基)乙基)苯基)哌啶-1-羧酸酯）、1-(2-fluoro-5-(hydroxymethyl)pyridin-4-yl)-3-(2-((3-formylphenyl) ethynyl)pyridin-4-yl)urea（1-(2-氟-5-(羥甲基)吡啶-4-基)-3-(2-(3-甲酰苯基)乙基)吡啶-4-基)尿素）?？捎糜谥苽洵h(huán)氧合酶(COX)(例如，環(huán)氧合酶2 (COX2))抑制劑化合物。這些化合物可以用放射性標(biāo)記，所述化合物(如放射性標(biāo)記化合物)可用于診斷疾病(如正電子發(fā)射斷層顯像劑)，這些化合物也可能對(duì)治療或預(yù)防疾病有用。

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